Bioforte Studies: Resveratrol
Bioforte | Abstract 5
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Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.
Cancer Letters Volume 245, Issues 1-2 , 8 January 2007, Pages 144-148
Sílvia Busquetsa, Elisabet Ametllera, Gemma Fustera, Mireia Olivana, Viktoria Raaba, Josep M. Argilésa and Francisco J. López-Soriano
Cancer Research Group, Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
Abstract:
Administration of different doses of the diphenol resveratrol had no effect on the growth of an intramuscularly implanted experimental tumour, the Lewis lung carcinoma. These results do not agree with previous reports where a clear effect of resveratrol was shown on tumour burden in both mice and rats. However, administration of the diphenol had a clear anti-metastatic effect, decreasing both the number and the weight of the lung metastases. Similar effects were observed both at 5 and 25 mg/kg body weight per day, resulting in an approximately 40% reduction in the number of metastases. These results suggest that resveratrol could be tentatively given as a preventive agent in cancer patients undergoing radiotherapy or chemotherapy.
The information contained above is protected by copyright. Wellness Plus has, where appropriate, obtained the permission of the copyright owner to publish the articles on this site. This permission does not convey to any third party.